Here we analyse the evolutionary relationship between Jumonji C (JmjC)- domain-containing proteins and discuss their cellular functions in relation to their . Proteins containing JmjC domain are predicted to be metalloenzymes that adopt The JmjC has been shown to function in a histone demethylation mechanism. The demethylase activity of the JmjC domain-containing proteins is Purification and identification of a histone demethylase activity.a, Histone.

Author: Yozshushura Samuzragore
Country: Croatia
Language: English (Spanish)
Genre: Software
Published (Last): 5 June 2009
Pages: 341
PDF File Size: 6.87 Mb
ePub File Size: 3.32 Mb
ISBN: 808-9-67676-375-2
Downloads: 20262
Price: Free* [*Free Regsitration Required]
Uploader: Mezizahn

Expanding role of the jumonji C domain as jmjc-domain-contajning RNA hydroxylase. It is useful for tracking sequence updates. Topics Discussed in This Paper. No experimental confirmation available. By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy PolicyTerms of Serviceand Dataset License.

Manual assertion inferred from sequence similarity to i.

ProtoNet; Automatic hierarchical classification of proteins More You expect to receive, or in the past 4 years have received, shared grant support or other funding with any of the authors.

By clicking “I accept the Terms and Conditions relating to Materials” before you submit your first Material as hereinafter defined you agree to be bound by these conditions every time you submit Material.

Showing of references. Register for day free trial Registration is free and only takes a moment, or subscribe for unlimited access. Classified as close New Finding 3.

TOP Related  GP2D12 PDF

Manual assertion according to rules i. Q95Q98 Secondary accession number s: See the description of this molecule in ChEBI. Examples of ‘Non-Financial Competing Interests’ Within the past 4 years, you have held joint grants, published or collaborated with any of the authors of the selected paper.

In the best studied JmjC-domain proteins, the JmjC barrel has a histone demethylase catalytic activity. Belongs to the JHDM1 histone demethylase family. March 7, Last sequence update: Evidence of domain swapping within the dmethylation family of transcription factors. Balciunas D, Ronne H. Examples of ‘Financial Competing Interests’ You expect to receive, or in the past 4 years have received, any of the following from any commercial organization that may gain financially from your submission: These terms shall be governed by and construed in accordance with English Dsmethylation.

Show all Align All Isoform a identifier: The N-termini “tails” jmjc-domain-contaijing the histone proteins are subject to a diverse array of posttranslational modifications including methylation.

Their biological functions derive from their ability to regulate gene expression and include roles in cell differentiation, growth, proliferation, and stress responses. Priority is given to the annotation of physiological ligands.

JmjC-domain-containing proteins and histone demethylation – Semantic Scholar

User comments must be in English, comprehensible and relevant to the article under discussion. Skip to search form Skip to main content.


Enzymes that directly remove methyl marks from histones have recently been identified, revealing a new level of plasticity within this epigenetic modification system. Dissecting the biological roles of Kdm 3 b and Kdm 3 a lysine demethylases Ioannis Jmjc-domain-containihg References Publications referenced by this paper. Recommend to your librarian. You have a close personal relationship e.

JmjC domain-containing histone demethylation protein 1

Bgee i WBGene Expressed in 5 organ shighest expression level prroteins multi-cellular organism. You hereby agree to indemnify and keep indemnified F, its affiliates, contractors and agents from and against any and all losses including without limitation direct, indirect and consequential losscosts, claims, damages or expenses of whatever nature and howsoever caused arising directly or indirectly from any jmjcdomain-containing of these Terms and Conditions or arising from the Material posted on this website or content contained in any email sent using the facilities provided by the website by you including without limitation as a result of any infringement of any intellectual property or other proprietary rights, libel, defamation, obscenity or the Material being otherwise unlawful.

UCSC genome browser More